Ever since she topped the Billboard Hot 100 with her debut track “Just Dance” in 2008, Lady Gaga has cemented herself as one of the greatest pop stars of the 21st century.

The success of “Just Dance” was not at all a fluke, it was actually an indicator of what was to come. Her follow-up track “Poker Face” also hit No. 1 on the Hot 100. Her debut album The Fame debuted at 17 on the Billboard 200 and rose to No. 2 on the chart after release of The Fame Monster. In the years after “Just Dance,” Gaga would continue to release some of the defining pop tracks of the century with songs like “Born This Way” and “Bad Romance.”

Lady Gaga has also made waves outside of pop music. Since her debut, she has released not one but two Grammy-winning jazz duet albums with legend Tony Bennett. In 2012, she started the Born This Way Foundation, a non-profit organization focused on tackling issues of youth mental health and bullying. In 2018, she wrote music for and starred in Bradley Cooper’s A Star is Born remake, earning her first Oscar nominations and a win for best original song. The following year, Gaga launched her makeup company Haus Labs, which has gone on to win several beauty awards for their innovative products.

Now, nearly two decades into her illustrious career, Gaga continues to ascend. In 2025, she released her seventh solo studio album MAYHEM, which topped the Billboard 200 and spawned six Hot 100 hits, including the No. 1 Bruno Mars duet “Die With a Smile.” The single spent five weeks at No. 1 and 60 weeks on the chart, and also made history as the first ever year-end Hot 100 No. 1 duet by a female and male soloist each in lead roles in the chart’s history. On top of the charts success, MAYHEM also brought Gaga her 15th and 16th Grammys with wins for best dance pop recording (for “Abracadabra”) and best pop vocal album at the 2026 awards.

On Saturday (March 28), Gaga will be celebrating her 40th birthday. To celebrate her milestone birthday, let’s take a trip down memory lane and look at Mother Monster’s 40 biggest Hot 100 hits thus far, below.

Lady Gaga’s biggest Billboard Hot 100 hits chart is based on performance on the weekly Billboard Hot 100, through the March 21, 2026, ranking. Songs are ranked based on an inverse point system, with weeks at No. 1 earning the greatest value and weeks at No. 100 earning the least. Due to changes in chart methodology over the years, eras are weighted to account for different chart turnover rates over various periods.